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Data Sets sometimes take up too much disk space. This technote describes how to obtain information about datasets and how to delete them.  

The WebSphere DataStage server has a centralized file for storing environment variables called  dsenv  in $DSHOME. $DSHOME identifies the WebSphere DataStage installation directory. The default directory is /opt/IBM/InformationServer/Server/DSEngine. You might need to add new environment variables as you configure WebSphere DataStage to connect to different databases using plug-ins or ODBC drivers. Any environment variables you need for interactive use of ODBC drivers to make a connection to an ODBC data source must be added to the  dsenv  file. This lets the WebSphere DataStage server inherit the proper environment for ODBC connections. For a connection using a wire protocol driver, there are no changes required to dsenv.

Below are the list of the things you will have to do to safely clean and restart your server. The first task (in UNIX and WINDOWS) that you will have to perform is to stop the Datastage services.  The services that have to be stopped are the dsrpc service,  dstelnet service, DSEngine service,  ASBAgent service and Logging Agent service.